Noteworthy changes in hichipper¶
Split .fastq files as input to HiC-Pro¶
As of version 0.5.3 of hichipper, users should be able to input split .fastq files into HiC-Pro
and have hichipper function properly. No extra user flags are needed for this functionality. Thanks
to our early users for helping us figure this out.
A note on duplicate PETs in loops¶
In certain versions (0.4.4 to 0.5.3) of hichipper, duplicates were not being filtered out
by default. These duplicates were potentially inflating the number of PETs mapping to loops only.
In version 0.7.1, peaks are now called using all reads without again filtering duplicates
as this is done during the HiC-Pro step.